
I have a male in the house, and I also have an in-season bitch in hte house at the moment. I can honestly say that I have coped really well until this season where he has been used. The whining is awful. He won't sit still for a second, so I will be sending him to my son's next time.
Before this season though, I managed without having too many problems. I had 2 cages set up. One for him and one for her. They were never let out together and the family were warned not to open a cage unless they were both in cages. The noise wasn't too bad, but he did whine on the optimum days (usually 3 to 4 days) It can be managed, but you have to be aware of the consequences if someone doesn't close doors. It's far easier to send one away, either to kennels or a member of a family that you can trust.
One other thing that you should take into consideration. Not all bitches will have regular seasons. She could be every 6 months on the dot, or she could be 5 months, or 7 months, or even a year, or a variation of all of these every time. In other words do be aware that she could come into season at the wrong time for you and your family. The boarding kennels could be fully booked, your brother could be on holiday abroad. As to when could she come in first time. I'm afraid no-one can predict that for you. Every bitch is different. 6 months is the earliest I would expect her to come in, but she could wait until almost 2 years old. Though most bitches that I know have come in by the time they are a year old.